Research Article
The Correlation between Chemical Composition, as Determined by UPLC-TOF-MS, and Acute Toxicity of Veratrum nigrum L. and Radix paeoniae alba
Table 2
Mice mortality after the intragastric administration of different proportion decoctions of V. nigrum L. and RPA.
| Group | V. nigrum L. dose (g) | RPA dose (g) | Crude drug concentration ratio | Female mortality | Male mortality | Total mortality |
| A | 6.415 | 0.6415 | 10 : 1 | 100% | 90% | 95% | B | 6.415 | 0.802 | 8 : 1 | 100% | 100% | 100% | C | 6.415 | 1.069 | 6 : 1 | 100% | 60% | 80% | D | 6.415 | 1.604 | 4 : 1 | 100% | 60% | 80% | E | 6.415 | 3.208 | 2 : 1 | 90% | 70% | 80% | F | 6.415 | 6.415 | 1 : 1 | 90% | 100% | 95% | G | 6.415 | 12.83 | 1 : 2 | 50% | 70% | 60% | H | 6.415 | 25.66 | 1 : 4 | 60% | 60% | 60% | I | 6.415 | 38.49 | 1 : 6 | 0 | 20% | 10% | J | 6.415 | 51.32 | 1 : 8 | 0 | 0 | 0 | K | 6.415 | 64.15 | 1 : 10 | 0 | 0 | 0 | L | 6.415 | 0 | 0 | 70% | 70% | 70% |
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