Research Article

The Correlation between Chemical Composition, as Determined by UPLC-TOF-MS, and Acute Toxicity of Veratrum nigrum L. and Radix paeoniae alba

Table 2

Mice mortality after the intragastric administration of different proportion decoctions of V. nigrum L. and RPA.

GroupV. nigrum L. dose (g)RPA dose (g)Crude drug concentration ratioFemale mortalityMale mortalityTotal mortality

A6.4150.641510 : 1100%90%95%
B6.4150.8028 : 1100%100%100%
C6.4151.0696 : 1100%60%80%
D6.4151.6044 : 1100%60%80%
E6.4153.2082 : 190%70%80%
F6.4156.4151 : 190%100%95%
G6.41512.831 : 250%70%60%
H6.41525.661 : 460%60%60%
I6.41538.491 : 6020%10%
J6.41551.321 : 8000
K6.41564.151 : 10000
L6.4150070%70%70%