Protective Effect and Mechanism of Total Flavones from Rhododendron simsii Planch on Endothelium-Dependent Dilatation and Hyperpolarization in Cerebral Ischemia-Reperfusion and Correlation to Hydrogen Sulphide Release in Rats

Table 1

Effect of TFR on cerebral H₂S level in rats subjected to cerebral ischemia-reperfusion.

Group	Dose (mg/kg)	𝑛	H2S (nmol/g)
Sham	—	8	11.5 ± 1.1
NS	—	8	17.6 ± 1.6**
TFR	25	8	19.8 ± 1.7^**#
	50	8	22.0 ± 2.3^**##
	100	8	25.6 ± 2.5^**##

^∗∗𝑃<0.01 compared to the sham control, ^#𝑃<0.05, ^##𝑃<0.01 compared to the NS control. Each group consisted of 8 rats. TFR: total flavones of Rhododendron simsii Planch, Sham: sham operation control group, and NS: normal saline control group.