Research Article
Anti-Trichophyton Activity of Protocatechuates and Their Synergism with Fluconazole
Table 3
Evaluation of IC50 and selectivity index of pentyl, hexyl, heptyl, octyl, and nonyl in NOK cells.
| | Substances | Cytotoxicity
IC50 (mg/L) | SI (IC50/MFC) | | Tr1 | Tr2 | Tr3 | Tm1 | Tm2 | Tm3 |
| | 7 | Pentyl | 57.0 | 7.3 | 7.3 | 7.3 | 3.7 | 7.3 | 7.3 | | 8 | Hexyl | 66.5 | 17.0 | 17.0 | 17.0 | 17.0 | 17.0 | 8.5 | | 9 | Heptyl | 78.1 | 40.0 | 40.0 | 40.0 | 20.0 | 80.5 | 20.0 | | 10 | Octyl | 54.0 | 27.7 | 7.0 | 27.7 | 13.8 | 27.7 | 13.8 | | 11 | Nonyl | 52.1 | 26.7 | 13.2 | 13.2 | 13.2 | 13.2 | 13.2 |
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