Prolonged Diuretic Activity and Calcium-Sparing Effect of Tropaeolum majus: Evidence in the Prevention of Osteoporosis
Figure 2
Prolonged HETM administration prevents the elevation of serum total cholesterol in OVX rats. Different groups of rats were treated for 4 weeks with HETM (3, 30, and 300 mg/kg), furosemide (C+, 25 mg/kg), or vehicle (C−). At the end of the experiment the animals were euthanized and their serum was collected for the determination of CT (a), HDL-C (b), LDL-C (c), and triglycerides (d). Each bar represents the mean of 7 animals and the vertical lines show the S.E.M. denotes significance levels compared with the group treated with vehicle alone (one-way ANOVA followed by Bonferroni test) ( ). TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol.
