Evaluation of Antioxidant Activity and Acute Toxicity of Clausena excavata Leaves Extract

Table 4

Effect of methanolic extract of Clausena excavata extract on liver biochemical parameters.

Treatment group; (MECE leaves)	ALT; (U/I)	AST; (U/I)	ALP; (U/I)	Albumin; (g/dL)	Bilirubin (µmol/L)
Male
CM	57.0^a ± 2.2	196.0^a ± 3.6	177.7^a ± 7.5	12.2^a ± 0.3	2.19^a ± 0.01
M1 (2000 mg/kg b.wt)	59.1^a ± 2.3	183.4^a ± 11.7	228.2^b ± 27.0	13.0^b ± 0.3	2.73^b ± 0.17
M2 (5000 mg/kg b.wt)	64.7^b ± 4.3	256.6^b ± 20.4	248.6^b ± 23.4	13.8^b ± 0.3	2.42^a ± 0.22
Female
CF	46.8^a ± 2.5	165.1^a ± 6.2	143.3^a ± 10.7	14.7^a ± 0.7	1.92^a ± 0.03
F1 (2000 mg/kg b.wt)	47.8^a ± 2.1	181.6^a ± 15.9	109.0^b ± 5.2	15.2^a ± 0.2	2.76^b ± 0.19
F2 (5000 mg/kg b.wt)	53.7^b ± 5.2	195.1^a ± 26.4	193.2^c ± 19.3	14.8^a ± 0.3	2.83^b ± 0.16

Values are mean ± SD.
^a,b,cFor each sex, means within column with different superscript are significant at < 0.05.
ALT = alanine transaminase; AST = aspartate transaminase; ALP = alkaline phosphatase.
MECE = methanolic extract Clausena excavata; CM = untreated control male; CF = untreated control female; M1, M2, F1, and F2 are treatment groups; b.wt = body weight.