Evaluation of Antioxidant Activity and Acute Toxicity of Clausena excavata Leaves Extract
Table 5
Effects of methanolic extract of Clausena excavata on kidney biochemical parameters.
Treatment Group (MECE leaves)
Sodium (mmol/L)
Potassium (mmol/L)
Chloride (mmol/L)
Urea (mmol/L)
Creatinine (umol/L)
Male
CM
144.31a ± 0.7
4.90a ± 0.10
104.8a ± 0.1
6.42a ± 0.34
635.6a ± 21.4
M1 (2000 mg/kg b.wt)
145.8b ± 0.2
4.66b ± 0.06
103.6b ± 1.0
4.61b ± 0.21
379.6b ± 48.7
M2 (5000 mg/kg b.wt)
146.2b ± 0.4
5.00b ± 0.25
105.0a ± 0.4
5.90c ± 0.21
415.5b ± 25.7
Female
CF
144.4a ± 0.7
4.70a ± 0.06
104.3a ± 1.1
5.79a ± 0.17
576.8a ± 31.1
F1 (2000 mg/kg b.wt)
144.2b ± 0.7
4.64a ± 0.29
104.4a ± 0.4
5.81a ± 0.24
424.6b ± 19.3
F2 (5000 mg/kg b.wt)
146.1b ± 0.9
4.90a ± 0.15
106.8b ± 0.6
7.70b ± 0.29
561.6a ± 29.8
Values are mean ± SD.
a,b,cFor each sex, means within column with different superscript are significant at < 0.05. MECE = methanolic extract Clausena excavata; CM = untreated control male; CF = untreated control female; M1, M2, F1, and F2 are treatment groups; b.wt = body weight.