Evaluation of Antioxidant Activity and Acute Toxicity of Clausena excavata Leaves Extract

Table 5

Effects of methanolic extract of Clausena excavata on kidney biochemical parameters.

Treatment Group; (MECE leaves)	Sodium; (mmol/L)	Potassium; (mmol/L)	Chloride; (mmol/L)	Urea; (mmol/L)	Creatinine; (umol/L)
Male
CM	144.31^a ± 0.7	4.90^a ± 0.10	104.8^a ± 0.1	6.42^a ± 0.34	635.6^a ± 21.4
M1 (2000 mg/kg b.wt)	145.8^b ± 0.2	4.66^b ± 0.06	103.6^b ± 1.0	4.61^b ± 0.21	379.6^b ± 48.7
M2 (5000 mg/kg b.wt)	146.2^b ± 0.4	5.00^b ± 0.25	105.0^a ± 0.4	5.90^c ± 0.21	415.5^b ± 25.7
Female
CF	144.4^a ± 0.7	4.70^a ± 0.06	104.3^a ± 1.1	5.79^a ± 0.17	576.8^a ± 31.1
F1 (2000 mg/kg b.wt)	144.2^b ± 0.7	4.64^a ± 0.29	104.4^a ± 0.4	5.81^a ± 0.24	424.6^b ± 19.3
F2 (5000 mg/kg b.wt)	146.1^b ± 0.9	4.90^a ± 0.15	106.8^b ± 0.6	7.70^b ± 0.29	561.6^a ± 29.8

Values are mean ± SD.
^a,b,cFor each sex, means within column with different superscript are significant at < 0.05.
MECE = methanolic extract Clausena excavata; CM = untreated control male; CF = untreated control female; M1, M2, F1, and F2 are treatment groups; b.wt = body weight.