Pharmacokinetics and Tissue Distribution Study of Chlorogenic Acid from Lonicerae Japonicae Flos Following Oral Administrations in Rats

<table>Representative mass spectrum of ChA and ibuprofen. (a1) Blank plasma sample of ChA. (a2) Blank plasma sample of ibuprofen. (b1) Standard calibration plasma sample with ChA at LLOQ level (7.820 <i>μ</i>g/L). (b2) Standard calibration plasma sample with ibuprofen at LLOQ level. (c1) Plasma sample after administration of LJF extract of ChA. (c2) Plasma sample after administration of LJF extract of ibuprofen. (d1) Liver sample of ChA. (d2) Liver sample of ibuprofen.</table>

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Figure 2

Figure 2: Pharmacokinetics and Tissue Distribution Study of Chlorogenic Acid from Lonicerae Japonicae Flos Following Oral Administrations in Rats 