Studies on the Antifatigue Activities of Cordyceps militaris Fruit Body Extract in Mouse Model
Table 3
The effects of Cordyceps militaris fruit body extract on skeletal muscle antioxidant status in mice before and after swimming.
Female
Male
CTRL
CM (g/kg)
Pro (g/kg)
CTRL
CM (g/kg)
Pro (g/kg)
0.5
1.0
2.0
0.5
0.5
1.0
2.0
0.5
Before swimming
MDA (nmol/mg prot)
0.78 ± 0.23
0.71 ± 0.19
0.77 ± 0.19
0.65 ± 0.20
0.73 ± 0.16
0.80 ± 0.25
0.75 ± 0.14
0.70 ± 0.19
0.69 ± 0.17
0.72 ± 0.16
ROS (FI/g prot)
15634 ± 1256
14569 ± 2012
15046 ± 2456
14569 ± 2178
14123 ± 1098
16023 ± 1891
15698 ± 2541
15036 ± 2013
15786 ± 1689
14563 ± 1048
SOD (U/mg prot)
113 ± 13
117 ± 19
1165 ± 13
115 ± 19
139 ± 30
117 ± 13
119 ± 27
117 ± 11
124 ± 11
157 ± 21
GSH-Px (mol/g prot)
10 ± 2
11 ± 3
13 ± 2
12 ± 2
11 ± 4
9 ± 2
11 ± 2
11 ± 3
13 ± 1
13 ± 1
After swimming
MDA (nmol/mg prot)
1.13 ± 0.46
0.77 ± 0.30
0.76 ± 0.31
0.69 ± 0.25
0.72 ± 0.34
1.16 ± 0.45
1.07 ± 0.42
0.62 ± 0.18
0.89 ± 0.13
0.79 ± 0.17
ROS (FI/g prot)
22108 ± 2918
17812 ± 2954
16933 ± 3149
15381 ± 138
17885 ± 5084
23018 ± 1491
22846 ± 1496
18057 ± 2310
17038 ± 2119
17313 ± 3852
SOD (U/mg prot)
98 ± 10
100 ± 10
116 ± 22
128 ± 9
117 ± 5
101 ± 5
98 ± 14
100 ± 10
111 ± 8
120 ± 9
GSH-Px (mol/g prot)
9 ± 2
13 ± 1
11 ± 3
14 ± 3
11 ± 2
9 ± 1
10 ± 1
11 ± 2
10 ± 2
11 ± 2
Treatment with Cordyceps militaris fruit body extract (0.5 g/kg, 1.0 g/kg, and 2.0 g/kg) and Rhodiola rosea (0.5 g/kg) for 2 weeks; before and after 20 min swimming, the levels of MDA, ROS, and the activities of SOD and GSH-Px in skeletal muscle in male and female mouse were detected. Values are expressed as mean ± S.D. ( = 6). and compared with control group.
