Research Article
Bathing Effects of Various Seawaters on Allergic (Atopic) Dermatitis-Like Skin Lesions Induced by 2,4-Dinitrochlorobenzene in Hairless Mice
Table 10
Splenic tissues histomorphometry after 6 weeks of continuous bathing on seawaters or topical application of DEXA in DNCB-induced AD mice.
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Values are expressed as mean ± SD of eight hairless mice. AD = allergic/atopic-like dermatitis; DNCB = 2,4-dinitrochlorobenzene; DEXA = dexamethasone-water soluble; WSSW = west surface seawater collected around Wepo-ri (Ganghwa-do, Republic of Korea); WSGW = west saline groundwater collected at Yonggungoncheon (Seokmo-do, Republic of Korea); ESSW = east surface seawater collected around Nagok-ri (Uljin, Republic of Korea); ESGW = east saline groundwater collected around Hoojeong-ri (Uljin, Republic of Korea); Th = thickness; IFN = interferon; IL = interleukin; iNOS = inducible nitric oxide synthase (); TNF = tumor necrosis factor. a and b as compared with intact control by MW test; c and d as compared with DNCB control by MW test. |