Tualang Honey Protects against BPA-Induced Morphological Abnormalities and Disruption of ERα, ERβ, and C3 mRNA and Protein Expressions in the Uterus of Rats

Figure 3

(a) Height of luminal epithelial cells of uterus in all experimental groups. BPA-induced reduction in luminal epithelial height (PC group) was significantly prevented by concurrent treatment with Tualang honey (TH group). Data are expressed as Mean ± SEM. (1) and versus NC (negative control). (2) versus PC (BPA 10 mg/kg). (3) and versus TH (Tualang honey 200 mg/kg + BPA 10 mg/kg). (4) versus THC (Tualang honey 200 mg/kg). (b) Thickness of endometrium of uterus in all experimental groups. BPA-induced reduction in thickness of the endometrium layer (PC group) was significantly prevented by concurrent treatment with Tualang honey (TH group). Data are expressed as Mean ± SEM. (1) versus NC (negative control). (2) , , and versus PC (BPA 10 mg/kg). (3) versus TH (Tualang honey 200 mg/kg + BPA 10 mg/kg). (4) versus THC (Tualang honey 200 mg/kg). (c) Thickness of myometrium of uterus in all experimental groups. BPA-induced reduction in the thickness of the myometrium layer (PC group) was significantly prevented by concurrent treatment with Tualang honey (TH group). Data are expressed as Mean ± SEM. (1) versus NC (negative control). (2) versus PC (BPA 10 mg/kg). (3) versus TH (Tualang honey 200 mg/kg + BPA 10 mg/kg). (4) versus THC (Tualang honey 200 mg/kg).

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