Research Article

Tualang Honey Protects against BPA-Induced Morphological Abnormalities and Disruption of ERα, ERβ, and C3 mRNA and Protein Expressions in the Uterus of Rats

Table 2

Body weight gain, uterine relative weight, malondialdehyde (MDA) level, and uterine histomorphometry parameters in all experimental groups.

GroupBody weight gain (g)Uterine relative weight (wet weight/body weight)Malondialdehyde (MDA) level (M/ protein)Height of luminal epithelial cells (m)Thickness of endometrium (m)Thickness of myometrium (m)

NC78.88 ± 14.611.89 ± 0.120.0037 ± 0.0002630.51 ± 1.37 571.87 ± 19.14299.18 ± 16.86
PC99.25 ± 9.901.41 ± 0.040.0074 ± 0.0005318.88 ± 0.81486.74 ± 10.15228.39 ± 8.91
THC89.5 ± 10.641.83 ± 0.070.0036 ± 0.0008928.23 ± 0.48574.25 ± 19.45299.26 ± 9.92
TH92.5 ± 4.621.73 ± 0.040.0049 ± 0.0006426.86 ± 0.68546.30 ± 3.78284.51 ± 16.63

Data are expressed as Mean ± SEM.
(1) and versus NC (negative control).
(2) , , and versus PC (BPA 10 mg/kg).
(3) and versus TH (Tualang honey 200 mg/kg + BPA 10 mg/kg).
(4) , , and versus THC (Tualang honey 200 mg/kg).