Review Article

Complementary and Alternative Therapies for Autism Spectrum Disorder

Table 13

Chiropractic care in ASD.

Author Year Type and duration of study Sample size Type of intervention ComparatorsOutcome measureFindings Comments

Aguilar et al. [91]2000Open label  
Duration: 9 months
Chiropractic careNoneModified Autism Checklist CARSImprovementNo control group  
Open label design  
Improvement potentially due to regression to the mean or normal development

Khorshid et al. [92]2006Randomized, parallel group  
Duration: 3–5 months
(M 13; F 1)  
Age: 4–16 years
Atlas Orthogonal Upper Cervical SMT  
Full spine SMT  
ATECImprovement (more in AO)Small sample size  
No control group  
Blinding not reported

ASD, autism spectrum disorder; ATEC, Autism Treatment Evaluation Checklist; CARS, Childhood Autism Rating Scale; SMT, Spinal Manipulative Therapy.