Research Article

A Standardized Traditional Chinese Medicine Preparation Named Yejuhua Capsule Ameliorates Lipopolysaccharide-Induced Acute Lung Injury in Mice via Downregulating Toll-Like Receptor 4/Nuclear Factor-κB

Table 1

Effects of YJH on TNF-, IL-1, and IL-6 levels.

GroupsTNF- (pg/mg protein)IL-1 (ng/mg protein)IL-6(ng/mg protein)

Sham31.97 ± 2.47 2.36 ± 0.225.52 ± 0.74
LPS123.7 ± 4 9.36#13. 41 ± 1.13#20.20 ± 2.47#
Dex (5 mg/kg)79.81 ± 13.56**5.28 ± 0.61**9.66 ± 1.57**
YJH (340 mg/kg)82.86 ± 7.83**6. 13 ± 0.53**11.74 ± 1.51**
YJH (170 mg/kg)91.71 ± 10.32**8.14 ± 0.71**13.96 ± 1.40**
YJH (85 mg/kg)112.49 ± 7.539. 35 ± 0.94*15.26 ± 1.22**

Data represented the mean ± SEM ( = 10). # < 0.01 compared to the sham group; * < 0.05 and ** < 0.01 compared to LPS group.