1,2,3,4,6-Penta-O-galloylglucose within Galla Chinensis Inhibits Human LDH-A and Attenuates Cell Proliferation in MDA-MB-231 Breast Cancer Cells

Figure 2

(a) Process of separation and isolation of hLDH-A inhibitor fractions from RCG. (b) hLDH-A inhibition by solvent extracts (PE: petroleum ether, EA: ethyl acetate). The data represent hLDH-A activity as % control and are expressed as the mean ± SEM, . (c) hLDH-A enzyme inhibition by further fractionation of the ethyl acetate fraction. The data represent hLDH-A activity as % control and are expressed as the mean ± SEM, . (d) hLDH-A enzyme inhibition by further fractionation of the ethyl acetate 167–215 fractions. The data represent hLDH-A activity as % control and are expressed as the mean ± SEM, .

(a)

(b)

(c)

(d)