The Chondroprotective Role of TMF in PGE₂-Induced Apoptosis Associating with Endoplasmic Reticulum Stress

Figure 3

Changes in CHOP, Bax, Bak, GRP78, and XBP1 mRNA expression. Chondrocytes in the control, the model group, and treated groups were incubated with 1 μM PGE₂ and 5, 10, and 20 μg/mL TMF for 48 h, respectively. The changes of mRNA expression of these genes were detected by qRT-PCR. GAPDH was used as internal control. Data were presented by mean ± SD of 4 replicates. as compared with the model.