Research Article

The Combined Extract of Zingiber officinale and Zea mays (Purple Color) Improves Neuropathy, Oxidative Stress, and Axon Density in Streptozotocin Induced Diabetic Rats

Table 3

Effect of PWCG on paw foot withdrawal threshold intensity evaluated by hot plate test test. (/group). -value< .001; compared to control rats. -value <.05, .01 and .001 respectively; compared to DM rats with CCI which received vehicle.

TimePaw withdrawal latency (sec)
ControlDM + CCI +
vehicle
DM + CCI + GABApentin
(50 mg·kg−1 BW)
DM + CCI + ascorbic acid
(100 mg·kg−1 BW)
DM + CCI + PWCG
(100 mg·kg−1 BW)
DM + CCI + PWCG
(200 mg·kg−1 BW)
DM + CCI + PWCG
(300 mg·kg−1 BW)

Baseline
Day 3
Day 6
Day 9
Day 12
Day 15
Day 18
Day 21