Study Duration of treatment Follow-up after treatment Experimental treatment Control treatment Cure rate of intervention group Cure rate of control group Outcome measurement Dong et al., 2012 [6 ] 5 weeks 6 months Acupoint injection with scraping therapy ( ) Western medicine: Meclofenoxate ( ) 46/60 (76.67%) 36/60 (60%) Cure rate, improvement rate, follow-up at 1 and 6 months Hong et al., 2011 [7 ] 1 month Not reported Moxibustion ( ) Acupuncture ( ) Chinese patent medicine ( ) 20/33 (60.6%) 19/33 (57.6%) 8/33 (24.24%) Cure rate, improvement rate Hui et al., 2006 [8 ] 1 month 1 year Heat-producing needling ( ) Western medicine: imipramine hydrochloride ( ) 20/35 (57.2%) 14/32 (43.8%) Cure rate, total effective rate, follow-up at 1 month Liu, 2007 [9 ] 3 weeks Not reported Enuresis patch ( ) Western medicine: Meclofenoxate ( ) 18/30 (60%) 9/30 (30%) Cure rate, improvement rate Karaman et al., 2011 [10 ] 4 weeks 6 months Laser acupuncture ( ) Placebo therapy: with a nonlaser light source ( ) 31/57 (54.4%) 3/26 (11.5%) Complete improvement rate, partial improvement rate, mean number of weekly bedwetting episodes: the children were reevaluated 15, 30, 90, and 180 days after treatment Ding et al., 2007 [11 ] 1 month 3 months Enuresis patch ( ) Western medicine: Meclofenoxate ( ) 25/42 (59.5%) 13/38 (34.2%) Cure rate, improvement rate Tong and Zhan, 2009 [12 ] 1 month Not reported Suspended moxibustion ( ) Chinese patent medicine ( ) 17/30 (56.7%) 10/30 (33.3%) Cure rate, improvement rate Moursy et al., 2014 [13 ] 3 months 6 months Laser acupuncture ( ) Western medicine: desmopressin ( ) Combination therapy: acupuncture + desmopressin ( ) 33 /62 (53%) 35/62 (56.5%) 46/82 (74%) Cure rate, improvement rate, mean weekly number of wet nights, MVV (maximum voided volume): the patients were evaluated once every 2 weeks for 3 months and once every 4 weeks for 6 months Tian and Zhong, 2008 [14 ] 2 weeks Not reported Acupuncture ( ) Chinese patent medicine ( ) 61/116 (52.59%) 47/112 (41.96%) Cure rate, improvement rate Ling and Chen, 2011 [15 ] 1 month Not reported Acupoint injection ( ) Chinese patent medicine ( ) 18/30 (60%) 15/30 (50%) Cure rate, improvement rate Radmayr et al., 2001 [16 ] 6 months Not reported Laser Acupuncture ( ) Western medicine: desmopressin ( ) 13/20 (65%) 15/20 (75%) Response rate, partial response rate Radvanska et al., 2011 [17 ] 5 weeks Not reported Laser acupuncture ( ) Placebo therapy: without active laser light but with or without skin contact ( ) Not reported not reported Wet nights/wk, voiding frequency, nocturnal urine production on wet nights MVV (maximal voided volume), AVV (average voided volume) Yang et al., 2012 [18 ] 1 month Not reported Ear point tapping with medicinal cake-separated moxibustion ( ) Chinese patent medicine ( ) 21/35 (60%) 12/34 (35.3%) Cure rate, improvement rate Luo, 2010 [19 ] 3 months Not reported Acupuncture-massage ( ) Chinese medicine ( ) 14/20 (70%) 4/20 (20%) Cure rate, improvement rate Tang et al., 2012 [20 ] 2 weeks 1 month Massage ( ) Chinese medicine ( ) 16/24 (66.7%) 11/24 (45.8%) Cure rate, improvement rate Qiu, 2008 [21 ] 1 month Not reported Ear point tapping ( ) Chinese medicine ( ) 17/31 (54.8%) 15/25 (60%) Cure rate, improvement rate Zhu et al., 2003 [22 ] 3 weeks 3 months Acupoint injection ( ) Western medicine: Meclofenoxate ( ) 19/41 (46.5%) 6/35 (17.1%) Cure rate, improvement rate Zhang, 2010 [23 ] 1 month Not reported Medicinal cake-separated moxibustion with embedded needling ( ) Western medicine: desmopressin ( ) 22/40 (55%) 6/40 (15%) Cure rate, improvement rate Chen and Gu, 2003 [24 ] 2 weeks Not reported Acupoint injection ( ) Chinese medicine ( ) 36/40 (90%) 14/32 (43.7%) Cure rate, improvement rate Yuksek et al., 2003 [25 ] 6 months Not reported Acupressure ( ) Western medicine: oxybutynin ( ) 10/12 (83.3%) 7/12 (58.3%) Complete improvement rate, partial improvement rate, follow-up at 15 days and 1, 3, and 6 months Hong and Zhang, 2009 [26 ] 1 month Not reported Needle warming moxibustion ( ) Chinese medicine ( ) 13/15 (86.7%) 5/15 (33.3%) Cure rate, improvement rate