Toxicopathological Evaluation of Hydroethanol Extract of Dianthus basuticus in Wistar Rats

Table 1

Effect of administration of hydroethanol extract of Dianthus basuticus on some weight parameters of male Wistar rats.

Parameters	Dose (mg/kg body weight/day)
	Control	200	400	800
Initial body weight (g)	257.10 ± 6.90	256.75 ± 3.98	240.81 ± 9.97	275.66 ± 4.22
Final body weight (g)	329.43 ± 6.22	328.66 ± 5.52	309.04 ± 2.94	317.85 ± 6.24
Relative liver weight (%)	3.20 ± 0.01	3.44 ± 0.02^***	3.21 ± 0.02	3.03 ± 0.01^***
Relative kidney weight (%)	0.63 ± 0.04	0.64 ± 0.02	0.58 ± 0.03^**	0.59 ± 0.02
Relative lung weight (%)	0.87 ± 0.04	0.85 ± 0.04	0.89 ± 0.04	1.00 ± 0.05^***
Relative spleen weight (%)	0.21 ± 0.02	0.19 ± 0.01	0.19 ± 0.01	0.19 ± 0.02
Relative heart weight (%)	0.28 ± 0.02	0.31 ± 0.02	0.30 ± 0.03	0.31 ± 0.01
Relative testis weight (%)	1.07 ± 0.06	1.11 ± 0.03	1.22 ± 0.05^***	1.15 ± 0.08^***

Values are presented as mean ± SEM ().
^**Statistically different from the control at .
^***Statistically different from the control at .