Research Article
Toxicopathological Evaluation of Hydroethanol Extract of Dianthus basuticus in Wistar Rats
Table 1
Effect of administration of hydroethanol extract of Dianthus basuticus on some weight parameters of male Wistar rats.
| Parameters | Dose (mg/kg body weight/day) | Control | 200 | 400 | 800 |
| Initial body weight (g) | 257.10 ± 6.90 | 256.75 ± 3.98 | 240.81 ± 9.97 | 275.66 ± 4.22 | Final body weight (g) | 329.43 ± 6.22 | 328.66 ± 5.52 | 309.04 ± 2.94 | 317.85 ± 6.24 | Relative liver weight (%) | 3.20 ± 0.01 | 3.44 ± 0.02*** | 3.21 ± 0.02 | 3.03 ± 0.01*** | Relative kidney weight (%) | 0.63 ± 0.04 | 0.64 ± 0.02 | 0.58 ± 0.03** | 0.59 ± 0.02 | Relative lung weight (%) | 0.87 ± 0.04 | 0.85 ± 0.04 | 0.89 ± 0.04 | 1.00 ± 0.05*** | Relative spleen weight (%) | 0.21 ± 0.02 | 0.19 ± 0.01 | 0.19 ± 0.01 | 0.19 ± 0.02 | Relative heart weight (%) | 0.28 ± 0.02 | 0.31 ± 0.02 | 0.30 ± 0.03 | 0.31 ± 0.01 | Relative testis weight (%) | 1.07 ± 0.06 | 1.11 ± 0.03 | 1.22 ± 0.05*** | 1.15 ± 0.08*** |
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Values are presented as mean ± SEM (). **Statistically different from the control at . ***Statistically different from the control at .
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