Toxicopathological Evaluation of Hydroethanol Extract of Dianthus basuticus in Wistar Rats
Table 4
Serum lipid profile of male Wistar rats administered with hydroethanol extract of Dianthus basuticus.
Parameters
Dose (mg/kg body weight/day)
Control
200
400
800
Total cholesterol (mmol/L)
1.46 ± 0.17
1.20 ± 0.07***
1.37 ± 0.15*
1.20 ± 0.04***
Triglycerides (mmol/L)
1.41 ± 0.13
1.60 ± 0.09***
1.62 ± 0.12***
0.88 ± 0.01***
HDL-C (mmol/L)
0.96 ± 0.03
1.07 ± 0.07**
0.99 ± 0.06
1.03 ± 0.06
LDL-C (mmol/L)
0.27 ± 0.06
0.27 ± 0.03
0.30 ± 0.01
0.20 ± 0.00
Atherogenic index
0.25 ± 0.01
0.27 ± 0.01
0.28 ± 0.01
0.22 ± 0.01
Values are presented as mean ± SEM (). *Statistically different from the control at . **Statistically different from the control at . ***Statistically different from the control at .