miRNA Regulation Network Analysis in Qianliening Capsule Treatment of Benign Prostatic Hyperplasia

Table 4

List of enriched GOs of differentially expressed mRNAs in BPH-1 cells treated with QC (2.5 mg/mL) and control cells.

ID	Definition	Gene count	P value
GO:0055114	Oxidation reduction	18
GO:0042127	Regulation of cell proliferation	15
GO:0006955	Immune response	14
GO:0042981	Regulation of apoptosis	14	0.002994
GO:0043067	Regulation of programmed cell death	14	0.00326
GO:0010941	Regulation of cell death	14	0.003365
GO:0008219	Cell death	12	0.009416
GO:0016265	Death	12	0.009889
GO:0012501	Programmed cell death	11	0.00846
GO:0010033	Response to organic substance	11	0.024364
GO:0043065	Positive regulation of apoptosis	10	0.002571
GO:0043068	Positive regulation of programmed cell death	10	0.002694
GO:0010942	Positive regulation of cell death	10	0.002778
GO:0009611	Response to wounding	10	0.009872
GO:0006915	Apoptosis	10	0.021064
GO:0030182	Neuron differentiation	9	0.009842
GO:0042493	Response to drug	8
GO:0044092	Negative regulation of molecular function	8	0.007664
GO:0022403	Cell cycle phase	8	0.022599
GO:0008284	Positive regulation of cell proliferation	8	0.022599

Enriched GOs were used for analysis of the differentially expressed mRNAs between two groups; values after multiple testing corrections <0.05.