Gray Matter Volumes in Patients with Chronic Fatigue Syndrome

Table 1

The gray matter volumes change in different researches.

Year	Title	Authors	Results
			Gray matter	Regions	White matter	Regions
2004	Mechanisms underlying fatigue, a voxel-based morphometric study of chronic fatigue syndrome	Okada et al. [34]	Reduction	Bilateral prefrontal	No significance
2005	Gray matter volume reduction in the chronic fatigue syndrome	de Lange et al. [36]	Reduction	Globe, no special regions	No significance
2008	Increase in prefrontal cortical volume following cognitive behavioural therapy in patients with chronic fatigue syndrome	de Lange et al. [37]	Increased	Lateral prefrontal	No significance
2011	A brain MRI study of chronic fatigue syndrome evidence of brainstem dysfunction and altered homeostasis	Barnden et al. [43]	No significance		No significance
2012	Regional grey and white matter volumetric changes in myalgic encephalomyelitis (chronic fatigue syndrome),; a voxel-based morphometry 3-T MRI study	Puri et al. [35]	Reduction	Occipital lobes, the right angular gyrus and the posterior division of the left parahippocampal gyrus	Reduction	Left occipital lobe