Research Article

Farnesol, a Sesquiterpene Alcohol in Herbal Plants, Exerts Anti-Inflammatory and Antiallergic Effects on Ovalbumin-Sensitized and -Challenged Asthmatic Mice

Table 5

Effects of farnesol supplementation with different doses for 5 weeks on inflammatory mediator and marker levels in BALF of OVA/AL-sensitized and -challenged BALB/c asthmatic mice.

Inflammatory mediator levels in BALF
GroupsNO (μM)Protein (μg/mL)Eotaxin (pg/mL)

DC95.89 ± 1.66 99.9 ± 12.4abc278 ± 130ab
FL115.22 ± 1.42 103 ± 22ab382 ± 109a
FM95.40 ± 1.33 106 ± 10a323 ± 159ab
FH116.42 ± 1.51 94.7 ± 12.7abc298 ± 73ab
PC115.68 ± 0.85 86.4 ± 7.6c241 ± 79b

NSC135.40 ± 1.42 90.0 ± 15.6bc270 ± 96ab

Values are means ± SD. Values within same column not sharing a common small letter are significantly different () from each other and assayed by one-way ANOVA, followed by Duncan’s new multiple range test. NSC, nonsensitized control; DC, dietary control; PC, positive control; FL, low dose farnesol (0.003% in AIN-76 feed); FM, medium dose farnesol (0.017% in AIN-76 feed); FH, high dose farnesol (0.067% in AIN-76 feed).