Gastroprotective Effect of Geopropolis from Melipona scutellaris Is Dependent on Production of Nitric Oxide and Prostaglandin

Figure 2

Effect of the p.o. administration of ethanolic extract of geopropolis (EEGP) on the ethanol induced ulcers. Rats pretreated subcutaneous (s.c.) with the N-ethylmaleimide 10 mg/kg (NEM). After 30 min, the rats were treated with vehicle (C and NEM) and with 300 mg/kg doses of EEGP. The results are expressed as means ± SEM, . Symbols indicate statistical difference (ANOVA followed by Tukey test, ). # compared to control (C) group and compared to control group.