Research Article
Comparison of Paeoniflorin and Albiflorin on Human CYP3A4 and CYP2D6
Figure 3
Effects of paeoniflorin and albiflorin on CYP3A4 and CYP2D6 mRNA expression. HepG2 cells, treated with paeoniflorin and albiflorin (10−5–10−7 M), were used to detect the variations of mRNA expressions of CYP isoenzymes. The mRNA expressions of CYP3A4 (a) and CYP2D6 (b) were analyzed by real-time RT-PCR. Values are means ± SD () and significant difference compared with control group; , albiflorin-treated groups versus control group.
(a) |
(b) |