The Anti-Porcine Parvovirus Activity of Nanometer Propolis Flavone and Propolis Flavone <i>In Vitro</i> and <i>In Vivo</i>

<div>The variation of sera IL-2, IL-6, and <i>γ</i>-IFN in every group after challenge (<i>μ</i>g⋅mL<sup>−1</sup>). <svg height="10.3145pt" id="M58" style="vertical-align:-0.04979992pt" version="1.1" viewbox="-0.0498162 -10.2647 16.0244 10.3145" width="16.0244pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0095,0,0,-0.0095,2.271,-5.984)"><path d="M433 39L423 65C413 59 399 54 387 54C370 54 352 69 352 114V299C352 352 342 392 307 422C285 440 255 449 225 449C168 437 102 399 75 379C56 365 44 353 44 339C44 315 69 296 87 296C101 296 111 303 116 319C124 349 133 371 145 385C156 397 171 404 190 404C241 404 275 364 275 291V274C253 256 180 229 120 209C65 190 39 159 39 110C39 47 88 -12 159 -12C189 -12 237 25 277 52C282 35 288 21 301 8C312 -3 333 -12 348 -12L433 39ZM275 84C256 65 221 48 195 48C164 48 124 73 124 124C124 161 146 180 185 198C206 208 254 229 275 240V84Z" id="g190-98"></path><glyph.data ascent="989" descent="-360" horiz-adv-x="439" vert-adv-y="439"></glyph.data></g><g transform="matrix(.0095,0,0,-0.0095,6.434,-5.984)"><path d="M469 201V252H50V201H469Z" id="g190-178"></path><glyph.data ascent="989" descent="-360" horiz-adv-x="520" vert-adv-y="520"></glyph.data></g><g transform="matrix(.0095,0,0,-0.0095,11.366,-5.984)"><path d="M390 111C344 68 312 56 269 56C212 56 118 102 118 241C118 346 175 401 241 401C277 401 312 388 342 360C350 352 355 349 361 349C372 349 394 371 394 392C394 403 391 411 378 422C362 436 329 449 288 449H287C250 449 190 432 138 392C71 341 37 274 37 197C37 90 112 -12 238 -12C297 -12 363 32 407 90L390 111Z" id="g190-100"></path><glyph.data ascent="989" descent="-360" horiz-adv-x="423" vert-adv-y="423"></glyph.data></g></svg>Bars in the same mode marked without the same superscripts differ significantly and <svg height="10.5763pt" id="M59" style="vertical-align:-0.04990005pt" version="1.1" viewbox="-0.0498162 -10.5264 8.68502 10.5763" width="8.68502pt" xmlns="http://www.w3.org/2000/svg" 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width="46.7259pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0135,0,0,-0.0135,0,0)"><path d="M600 480C600 590 528 650 384 650H143L137 622C222 614 225 607 210 531L130 127C113 41 106 36 23 28L17 0H294L300 28C204 36 195 42 212 127L243 284L314 263C327 263 339 263 352 264C465 271 600 337 600 480ZM508 481C508 351 402 304 329 304C289 304 265 311 250 317L295 559C302 594 310 606 323 611C335 616 350 619 367 619C455 619 508 573 508 481Z" id="g113-81"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="617" vert-adv-y="617"></glyph.data></g><g transform="matrix(.0135,0,0,-0.0135,12.15,0)"><path d="M512 -3V55L134 254V256L512 456V514L75 281V230L512 -3Z" id="g117-91"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="587" vert-adv-y="587"></glyph.data></g><g transform="matrix(.0135,0,0,-0.0135,23.887,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 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NPF, nanometer propolis flavone; PF, propolis flavone; DoseH, high dose; DoseM, middle dose; DoseL, low dose; CC, challenged control; BC, blank control. (a) The variation of serum IL-2; (b) the variation of serum IL-6; (c) the variation of serum <i>γ</i>-IFN.</div>

Evidence-Based Complementary and Alternative Medicine

fig6

Figure 6

Figure 6: The Anti-Porcine Parvovirus Activity of Nanometer Propolis Flavone and Propolis Flavone <i>In Vitro</i> and <i>In Vivo</i> 

Evidence-Based Complementary and Alternative Medicine

The Anti-Porcine Parvovirus Activity of Nanometer Propolis Flavone and Propolis Flavone In Vitro and In Vivo

Figure 6