Vitis vinifera (Muscat Variety) Seed Ethanolic Extract Preserves Activity Levels of Enzymes and Histology of the Liver in Adult Male Rats with Diabetes

Table 3

Semiquantitative analyses of histopathological changes of the liver.

Parameters	Normal	Diabetic	Diabetic
			250 mg/kg; V. vinifera	500 mg/kg; V. vinifera	600 μg/kg; glibenclamide
Necrosis	0	++	+	+	+
Sinusoidal; hyperemia	0	++	++	+	0
Connective tissue inflammation in portal region	0	++	+	0	0

0: no changes, +: mild changes, ++: moderate changes, and +++: severe changes.