In Vitro and In Vivo Anticancer Activity of Root Extracts of Sansevieria liberica Gerome and Labroy (Agavaceae)

Table 3

Effects of SL-A002 extract against Sarcoma-180 solid tumor in BALB/c mice.

Treatments	Dose (mg/kg)	Body weight (g); Day 1	Body weight (g); Day 5	Body weight (g); Day 9	Body weight (g); Day 13	Tumor volume (mm^3); Day 9	Inhibition (%); Day 9	Tumor volume (mm^3); Day 13	Inhibition (%); Day 13
Normal saline	(0.2 mL/mouse)	21.80 ± 0.58	23.00 ± 0.55	23.80 ± 0.58	24.00 ± 0.32	1848.50 ± 108.31	0.00	2283.50 ± 136.58	0.00
5-FU	20	21.80 ± 0.58	20.60 ± 1.17	18.80 ± 2.08^a	19.80 ± 2.15	676.80 ± 188.15^c	63.39	1137.60 ± 247.45^b	50.18
SL-A002	100	21.20 ± 0.66	19.20 ± 0.80^b	19.60 ± 0.87^b	19.80 ± 0.73^b	861.10 ± 157.60^c	53.42	1201.20 ± 232.26^b	47.40

Values are mean ± SEM (). , , and versus normal saline.