Effects of Electroacupuncture on Chronic Unpredictable Mild Stress Rats Depression-Like Behavior and Expression of p-ERK/ERK and p-P38/P38

Table 1

Unpredictable stressors for 14 days.

Day	Time of 1st stressor	1st stressor	Time of 2nd stressor	2nd stressor
1	10:00 a.m.	10°C swim stress (4 min)	4:00 p.m.	Lights off (2 h)
2	12:30 p.m.	Lights off (3 h)	7:00 p.m.	Lights on overnight
3	10:00 a.m.	4°C cold isolation (20 min)	4:00 p.m.	Cage shaking (5 min)
4	11:00 a.m.	4°C cold isolation (1 h)	2:00 p.m.	Restraint stress (40 min)
5	3:00 p.m.	Lights off (2 h)	5:00 p.m.	Cage tilting 45° (2 h)
6	10:00 a.m.	Food deprivation (24 h)
7	10:00 a.m.	Water deprivation (24 h)
8	3:30 p.m.	10°C swim stress (15 min)	7:00 p.m.	Lights on overnight
9	4:00 p.m.	Restraint stress (1 h)	5:00 p.m.	Lights off (1 h)
10	10:00 a.m.	Cage shaking (5 min)	3:30 p.m.	4°C cold isolation (15 min)
11	12:00 p.m.	Lights off (2 h)	7:00 p.m.	Lights on (2 h)
12	10:00 a.m.	Restraint stress (1 h)	2:00 p.m.	10°C swim stress (5 min)
13	10:00 a.m.	Food deprivation (24 h)
14	10:00 a.m.	Water deprivation (24 h)