Review Article

Tai Chi Chuan for the Primary Prevention of Stroke in Middle-Aged and Elderly Adults: A Systematic Review

Table 1

The Characteristics of Included Studies in This Systematic Review.

Author, yearMethods Participants total (T/C)Mean (SD)/range age; subjectsInterventionFrequency and duration of TCC intervention Outcomes
TreatmentControl

Ding and Yang 2006 [23] RCT60 (30/30)mean 65/66 (T/C) years; Hyperlipidemia patientsTCCNonintervention50 minutes per time and 5 times a week for 20 weeksTC, TG, HDL-C, LDL-C
Liu and Zhang 2001 [24] RCT86 (44/42)mean age: 64.8 years; Healthy eldersTCCNoninterventionabove 60 minutes per time and twice a day for more than 48 weeksBMI, TC, TG, HDL-C, LDL-C
Ma and Dong 2011 [25] RCT30 (15/15)middle-aged and elderly adults Hyperlipidemia patientsTCCNonintervention60 minutes every day for 24 weeksTC, TG, HDL-C, LDL-C
Mao et al. 2007 [26] RCT80 (40/40)mean 63 years; Healthy elderly womenTCCNonintervention45 to 60 minutes per time and 3 times a day for 48 weeksTC, TG, HDL-C, LDL-C
Sha 2007 [27] RCT40 (20/20)mean 64.5/63.4 (M/W) years; Healthy eldersTCC Nonintervention60 to 120 minutes per time and 5 to 7 times a week for 72 weeksTC, TG, HDL-C, LDL-C
Wang 2010 [28] RCT85 (40/45)Mean 56.46/56.34 (T/C) years; Healthy elderly womenTCC Nonintervention30 minutes per time and 4 times a week for 18 weeksSBP, DBP
Wu et al. 2010 [29] RCT40 (20/20)mean 51.3/52.4 (T/C) years; Healthy eldersTCCNoninterventionabove 60 minutes per time and above 3 times a week for 24 weeksSBP, DBP, FBG, FPI
Yan and Zhang 2006 [30] RCT32 (16/16)mean 50.5/50.8 (T/C) years; Healthy eldersTCCNoninterventionabove 30 minutes per time, once a day and 5 to 7 times a week for 48 weeksTC, TG, FBG, PBG
Zhang and Fu 2008 [31] RCT20 (10/10)mean 57.4 ± 6.2 years; Type 2 diabetes patientsTCC Nonintervention60 minutes a day, and 5 times a week for 14 weeksTC, TG, HDL-C, LDL-C, FBG, FPI
Zhou 2007 [32] RCT120 (60/60)mean 52.3/53.4 (T/C) years; Type 1 EH patientsTCC Nonintervention60 minutes a day for 12 weeksSBP, DBP, TC, TG, HDL-C, LDL-C
Han 2010 [33] SC50mean 60.5/61.7 (M/W) years; Healthy elders TCC Nonintervention60 minutes per time and mean 4 times per week for 24 weeksSBP, DBP
Lei et al. 2001 [34] SC39mean 61.87 years; Healthy eldersTCC Nonintervention30 minutes per time and once or twice a day for 48 weeksSBP, DBP
Han 2012 [35] NRCT25 (15/10)mean 61.2/57.1 (T/C) years; Healthy eldersTCCNonintervention60 minutes per time and 3 times a week for 12 weeks.Weight, BMI, WHR, SBP, DBP, TC, TG, HDL-C, LDL-C, FBG
Rosado-Pérez et al. 2013 [36] NRCT25 (15/10)mean 66.4/66.7 (T/C) years; Healthy elders TCCNonintervention60 minutes every day for 24 weeksBMI, SBP, DBP, TC, TG, HDL-C, LDL-C, FBG
Li et al. 2007 [37] NRCT32 (16/16)mean 58 years; Healthy eldersTCC Nonintervention45 minutes per time, 5 times a day at learning phase of 4 weeks and 60 minutes per time, 5 times a day at practice period of 20 weeks.TC, TG, HDL-C, LDL-C
Li et al. 2010 [38] NRCT156 (79/77)mean 67.44/69.40 (T/C) years; Healthy eldersTCC Noninterventionabove 30 minutes per time and above 3 times a day for more than 24 weeksWeight, BMI, SBP, DBP
Liu and Jin 2010 [39] NRCT20 (10/10)range from 53 to 68 years; Healthy eldersTCCNonintervention60 minutes per time and 4 times per week for 8 weeksSBP, DBP
Liu and Zhang 2001 [40] NRCT69 (36/33)range from 60 to 71 years; Healthy eldersTCCNoninterventionfor 2 yearsHDL-C, LDL-C
Meng 2010 [41] NRCT36 (25/11)mean 49.4/47.09 (T/C) years; Healthy eldersTCC Noninterventionabove 14 hours a week and mean time of exercise is 14.7 ± 8.6 monthsLDL-C
Si 2006 [42] NRCT60 (30/30)mean 55.3/56.6 (T/C) years; Healthy eldersTCCNonintervention40 to 60 minutes per time and above 4 times a week for more than 2 yearsBMI, SBP, DBP, TC, TG, HDL-C, LDL-C, FBG
Xu and Wen 1997 [43] NRCT34 (18/16)mean 66.7/64.6 (T/C) years; Healthy eldersTCC Nonintervention30 minutes per time and twice a day for 4 weeksSBP, DBP
Yang and Fu 2010 [44] NRCT60 (30/30)range from 50 to 70 years; Healthy elderly menTCC Nonintervention90 minutes per time and more than 4 times per week for 48 weeks Weight, SBP, DBP
Chen 2013 [45] RCT60 (32/28)mean 69.3/68.7 (T/C) years; CHD patients TCC plus conventional treatmentThe same conventional treatment60 minutes per time and 4 times a week for 12 weeksTC, TG, HDL-C, LDL-C
Chen and Lv 2006 [46] RCT40 (20/20) mean 64.3/60 (T/C) years; EH patientsTCC plus conventional treatmentThe same conventional treatment40 minutes every day for 9 weeksSBP, DBP
Chen and Lv 2013 [47] RCT68 (50/18)range from 30 to 82 years; EH patientsTCC plus conventional treatmentsame conventional treatment30 minutes per time and 6 times a week for 12 weeksSBP, DBP
Han et al. 2010 [48] RCT60 (30/30)mean 62.12 years; EH patientsTCC plus routine treatmentThe same routine treatment45 to 60 minutes per time and 1 to 2 times a week for 48 weeksSBP, DBP, incidence of fatal, non-fatal stroke and cardiac failure
Li et al. 2006 [49] RCT38 (20/18)mean 66/67 (T/C) years; CHD patientsTCC plus conventional treatmentThe same conventional treatment40 minutes per time, twice a day and above 6 times a week for 24 weeksLDL-C
Lin 2012 [50] RCT60 (30/30)mean 60 years; Type 2 diabetes patientsTCC plus conventional treatmentThe same conventional treatment90 minutes every day for 12 weeksSBP, DBP
Luo 2006 [51] RCT84 (44/40)mean 44.74/44.84 (T/C) years; EH patients TCC plus conventional treatmentThe same conventional treatment45 minutes per time and once a day for 24 weeksSBP, DBP
Mao and Sha 2006 [52] RCT62 (51/11)mean 62.2/63.3 (T/C) years; EH patientsTCC plus conventional treatmentThe same conventional treatment60 minutes per time and 6 time a week for 8 weeksSBP, DBP
Tang 2009 [53] RCT32 (16/16)mean 63.65/62.79 (T/C) years; EH patients TCC plus conventional treatmentThe same conventional treatment30 to 60 minutes per time and 3 to 5 times a week for 24 weeksSBP, DBP
Wang et al. 2011 [54] RCT60 (30/30)range from 50 to 70 years; Type 2 and 3 EH patientsTCC plus conventional treatmentThe same conventional treatment120 minutes per time and 5 times a week for 16 weeksSBP, DBP
Xiao et al. 2011 [55] RCT24 (12/12)mean 55 ± 4.12 years; Type II diabetes patientsTCC plus conventional treatmentThe same conventional treatment60 minutes per time, once a day and 6 times a week for 24 weeksFBG
Yu 2004 [56] RCT40 (20/20)mean 50/49 (T/C) years; Type II diabetes and EH patientsTCC plus conventional treatmentThe same conventional treatment60 minutes per time and once a day for 12 weeksFBG, FPI
Chen et al. 2011 [57] RCT441 (238/203)range from 35 to 75 years; EH patientsTCC plus conventional treatment plus health educationThe same conventional treatment plus same health education60 minutes per time and 5 times a week for 2 yearsSBP, DBP
Zeng et al. 2012 [58] NRCT125 (63/62)range from 45 to 70 years; Healthy eldersTCC plus health educationThe same health education30 to 40 minutes per time, and no less than 3 times a week for 2 yearsWeight, waistline, hip circumference, SBP, DBP, incidence of fatal, non-fatal stroke and CCD

BMI: body mass index; CCD: cardia-cerebrovascular disease; CHD: coronary heart disease; DBP: diastolic blood pressure; EH: essential hypertension; FBG: fasting blood glucose; FPI: fasting plasma insulin; HDL: high-density lipoprotein; LDL: low-density lipoprotein; M/W: man/woman; NRCT: prospective nonrandomized controlled trial; PBG: postprandial two-hour blood glucose; RCT: randomized controlled trial; SC: self-controlled trial; SBP: systolic blood pressure; TCC: Tai Chi Chuan; T/C: treatment/control; TC: total cholesterol; TG: triglycerides; WHR: waist-hip rate.