Evidence-Based Complementary and Alternative Medicine / 2015 / Article / Tab 1 / Research Article
Inhibitory Effects of Cytosolic Ca2+ Concentration by Ginsenoside Ro Are Dependent on Phosphorylation of IP3 RI and Dephosphorylation of ERK in Human Platelets Table 1 Effects of Rp-8-Br-cAMPS and Rp-8-Br-cGMPS on [Ca
2+ mobilization.
[Ca2+ (nM) Increase (%) G-Ro (155 μ M) + thrombin (0.05 U/mL) 160.3 ± 8.1 — G-Ro (155 μ M) + Rp-8-Br-cAMPS (250 μ M) + thrombin (0.05 U/mL) 326.3 ± 9.0 103.6(1) G-Ro (155 μ M) + Rp-8-Br-cGMPS (250 μ M) + thrombin (0.05 U/mL) 202.6 ± 4.6 26.4(2) G-Ro (300 μ M) + thrombin (0.05 U/mL) 140.1 ± 1.8 — G-Ro (300 μ M) + Rp-8-Br-cAMPS (250 μ M) + thrombin (0.05 U/mL) 260.3 ± 9.9 85.8(1) G-Ro (300 μ M) + Rp-8-Br-cGMPS (250 μ M) + thrombin (0.05 U/mL) 191.8 ± 7.3 36.9(2)
Data were from Figures 4(b) and 4(c) . (1) Increase (%) = [(G-Ro + thrombin + Rp-8-Br-cAMPS) − (G-Ro + Thrombin)]/(G-Ro + thrombin) × 100, (2) increase (%) = [(G-Ro + thrombin + Rp-8-Br-cGMPS) − (G-Ro + thrombin)]/(G-Ro + thrombin) × 100.