Primo Vascular System: An Endothelial-to-Mesenchymal Potential Transitional Tissue Involved in Gastric Cancer Metastasis

Figure 6

Intermediate state of metastasis between primo vessel-mediated metastasis and vascular vessel-mediated metastasis. (a) Intermediate metastatic tumors between primo vessel-mediated metastasis and blood vessel-mediated metastasis were detected. Half of the tumor showed white color (black arrow) and the other part showed orange color (black arrowhead). (b) Lifting the metastatic tumor in (a); a free, semitransparent, and thread-like structure was detected (black arrow). (c) Magnification of metastatic tumor; red blood vessels and capillaries were obvious (black arrow). (d) Under the LZ12 microscope, high GFP fluorescence was expressed in the proximal part of metastatic tumor (yellow arrow) while lower GFP fluorescence was expressed in the distal part (yellow arrowhead).

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