Effect of Luteolin on 11Beta-Hydroxysteroid Dehydrogenase in Rat Liver and Kidney

Figure 3

Effects of Luteolin on the protein expression of 11β-HSD I and 11β-HSD II in rat liver (a and b) and kidney (c and d). Rats were orally administrated with vehicle (CMC-Na) or Luteolin (5 mg/kg, 10 mg/kg, or 20 mg/kg) for 14 days. Liver and kidney were harvested and then 11β-HSD I and 11β-HSD II protein levels were analyzed. Data are expressed as fold change over the control group (mean ± SD, ) , . 1, 2: control group; 3, 4: Luteolin 5 mg/kg; 5, 6: Luteolin 10 mg/kg; 7, 8: Luteolin 20 mg/kg.

(a) Liver

(b) Liver

(c) Kidney

(d) Kidney