Yokukansan Improves Mechanical Allodynia through the Regulation of Interleukin-6 Expression in the Spinal Cord in Mice with Neuropathic Pain

Figure 1

Mechanical allodynia in mice with partial sciatic nerve ligation (PSL). PSL or a sham operation was performed on day 0. Mechanical allodynia was tested by punctate stimulation using a von Frey filament with a bending force of 0.16 g applied to the footpad of the paw on the PSL side. Data are presented as means ± standard errors of the means (). compared with the sham mice (Holm-Sidak test).