Eye Acupuncture Treatment for Stroke: A Systematic Review and Meta-Analysis

Table 2

Estimated effect sizes of included trials in meta-analyses.

Trials	Participants	Estimate effects
() Changes of CSS scores for neurological assessment
() Eye acupuncture combined with western medicine versus western medicine
Wang et al. (2008) [9]	120	MD −5.56 [−7.15, −3.97]
Cui (2009) [13]	18	MD −3.23 [−9.14, 2.68]
Li (2010) [14]	48	MD −2.44 [−5.44, 0.56]
Wang et al. (2007) [15]	90	MD −3.84 [−5.35, −2.33]
Subtotal MD −4.24, 95% CI −5.59 to −2.89 = 31% fixed
() Eye acupuncture combined with TCM herbal treatment versus TCM herbal treatment
Liu (2010) [11]	56	MD −2.89 [−4.15, −1.63]
() Eye acupuncture combined with rehabilitation versus rehabilitation
Jiang (2009) [20]	60	RR −2.40 [−4.87, 0.07]
() Eye acupuncture combined with rehabilitation and western medicine versus rehabilitation combined with western medicine
Gao (2012) [22]	60	MD −2.40 [−3.76, −1.04]
() Changes of ADL at the end of treatment
() Eye acupuncture combined with rehabilitation and western medicine versus rehabilitation combined with western medicine
Chen et al. (2007) [17]	80	MD 17.60 [14.19, 21.01]
() Eye acupuncture combined with western medicine versus western medicine
Gao (2012) [22]	60	MD 4.67 [1.45, 7.89]
() Changes of SSS score at the end of treatment
() Eye acupuncture combined with rehabilitation and western medicine versus rehabilitation combined with western medicine
Chen et al. (2007) [17]	80	MD 12.41 [8.92, 15.90]
() Changes of FMA assessment at the end of treatment
() Eye acupuncture combined with rehabilitation and western medicine versus rehabilitation combined with western medicine
Chen et al. (2007) [17]	80	MD 8.31 [3.15, 13.47]
() Changes of HAMD score at the end of treatment
() Eye acupuncture combined with western medicine versus western medicine
Huang (2013) [23]	156	MD −0.82 [−1.87, 0.23]
() Changes of MMSE assessment at the end of treatment
() Eye acupuncture combined with western medicine versus western medicine
Li (2009) [18]	50	MD 1.60 [0.28, 2.92]
() Changes of SWT assessment at the end of treatment
() Eye acupuncture combined with western medicine versus western medicine
Li and Wang (2009) [16]	100	RR 1.24 [1.03, 1.49]
() Changes of NDS
() Eye acupuncture combined with western medicine versus western medicine
Zhou et al. (2011) [10]	120	RR 1.08 [0.93, 1.26]
() Constipation symptoms evaluation at the end of treatment
() Eye acupuncture combined with rehabilitation and western medicine versus rehabilitation combined with western medicine
Xi (2011) [19]	60	MD −4.78 [−5.14, −4.42]
() First defecation time at the end of treatment
() Eye acupuncture combined with rehabilitation and western medicine versus rehabilitation combined with western medicine
Xi (2011) [19]	60	MD −1.03 [−1.46, −0.60]
() Changes of ET level at the end of treatment
() Eye acupuncture combined with western medicine versus western medicine
Zhou et al. (2011) [10]	120	MD −7.03 [−9.48, −5.12]
Li (2010) [14]	48	MD 68.27 [61.03, 75.51]
Subtotal 168 MD 30.40 95% CI −43.65 to 104.46 = 100% random
() Eye acupuncture combined with rehabilitation versus rehabilitation
Cui (2009) [13]	18	MD −10.71 [−28.09, 6.67]
() Eye acupuncture versus rehabilitation
Xu et al. (2006) [24]	60	MD −0.64 [−1.17, −0.12]
() Changes of CGRP level at the end of treatment
() Eye acupuncture combined with western medicine versus western medicine
Zhou et al. (2011) [10]	120	MD 5.67 [4.03, 7.31]
Li (2010) [14]	48	MD 1.48 [−5.31, 8.27]
Subtotal 168 MD 1.48 95% CI −5.31 to 8.27 = 28% fixed
() Changes of FIB level at the end of treatment
() Eye acupuncture combined with western medicine versus western medicine
Wang et al. (2008) [9]	120	MD −0.72 [−1.09, −0.35]
() Changes of CRP level at the end of treatment
() Eye acupuncture combined with western medicine versus western medicine
Wang et al. (2007) [15]	90	MD −5.86 [−7.54, −4.18]
()  Changes of VEGF level at the end of treatment
() Eye acupuncture versus western medicine
Dong (2009) [25]	60	MD 0.02 [−0.49, 0.53]