Antibacterial and Cytotoxic Activity of Compounds Isolated from Flourensia oolepis

Figure 4

Effects of compound 1 on cell death process. CCRF-CEM and K562 cells were incubated for 72 h with 1% ethanol (controls (a) and (c), resp.) or with 2 × IC₅₀ of 1 ((b) and (d), resp.). Apoptotic effect of 1 was evaluated by flow cytometry analysis after double staining with Annexin V-APC and PI. Annexin V-APC intensity is represented on the -axis and PI fluorescence intensity is represented on the -axis.

(a)

(b)

(c)

(d)