Research Article
The Triterpenoid Betulin Protects against the Neuromuscular Effects of Bothrops jararacussu Snake Venom In Vivo
Table 2
Osmolality of injectable betulin solutions.
| | CBA | Betulin
(mg) | PEG 400
(µL) | Sterile saline
(final volume: 1 mL) | Osmolality
(mOsmol/kg) |
| | 1 mL | — | — | — | 421 | | — | — | 15 | 985 µL | 343 | | — | — | 45 | 955 µL | 421 | | — | — | 90 | 910 µL | 617 | | — | — | 135 | 865 µL | 802 | | — | — | 225 | 775 µL | 3148 | | — | — | 300 | 700 µL | 3143 | | — | 1 | 15 | 985 µL | 323 | | — | 3 | 45 | 955 µL | 524 | | — | 6 | 90 | 910 µL | 547 | | — | 9 | 135 | 865 µL | 939 | | — | 15 | 225 | 775 µL | 3120 | | — | 20 | 300 | 700 µL | 3092 |
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The osmolality values are the mean of duplicate determinations that varied by ≤10%.
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