Research Article
The Protective Effect of Lacidipine on Myocardial Remodeling Is Mediated by the Suppression in Expression of GPR78 and CHOP in Rats
Table 3
Semiquantitative analysis of GRP78 and CHOP expression in myocardial tissue detected by immunohistochemistry.
| Group | GRP78 (optical density) | CHOP (optical density) |
| Normal blank group | 0.25 ± 0.02 | 0.08 ± 0.02 | SHR control group | 0.36 ± 0.04* | 0.49 ± 0.07* | Captopril positive control group | 0.29 ± 0.02# | 0.25 ± 0.03# | Lacidipine 1.44 mg/kg group | 0.31 ± 0.03 | 0.32 ± 0.04 | Lacidipine 0.72 mg/kg group | 0.30 ± 0.02# | 0.27 ± 0.03# | Lacidipine 0.36 mg/kg group | 0.33 ± 0.03 | 0.36 ± 0.04 |
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< 0.05 compared with normal blank group; # < 0.05 compared with SHR control group.
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