GABA-A Receptor Modulation and Anticonvulsant, Anxiolytic, and Antidepressant Activities of Constituents from Artemisia indica Linn

Table 3

Effect of carnosol, ursolic acid, and oleanolic acid in locomotor activity test.

Group	Treatment	Dose (mg/kg)	Line-crossing counts (mean ± SEM)
1	Control	—	44.6 ± 6.5
2	Carnosol	10	45.4 ± 3.5
3		30	43.7 ± 5.3
4		100	36.5 ± 3.2
5	Ursolic acid	10	45.4 ± 3.5
6		30	43.3 ± 2.4
7		100	35.9 ± 4.5
8	Oleanolic acid	10	40.8 ± 2.2
9		30	42.3 ± 3.3
10		100	34.6 ± 4.1
11	Imipramine	60	40.2 ± 2.6
12	Diazepam	1	35.5 ± 3.5

All values are expressed in mean ± SEM (). compared to the vehicle group. Differences between groups were analyzed by analysis of variance (one-way ANOVA) followed by Dunnett’s test.