Research Article

Investigation of Calcium Channel Blockers as Antiprotozoal Agents and Their Interference in the Metabolism of Leishmania (L.) infantum

Figure 1

Action of amlodipine and fendiline in the mitochondrial membrane potential. Alterations in mitochondrial membrane potential were evaluated in L. (L.) infantum promastigotes after treatment with amlodipine and fendiline (20 μM), using the fluorescent probe MitoTracker Red. Untreated parasites were used as negative control, while parasites treated with nitazoxanide were used as positive control. () indicates significant difference relative to the untreated group (; ).