Research Article

In Vivo Interrelationship between Insulin Resistance and Interferon Gamma Production: Protective and Therapeutic Effect of Berberine

Table 2

Effect of HFD alone or combined with berberine on insulin resistance.

GroupsBody weight (gm)Glucose (mg/dL)Insulin (µU/mL)HOMA-IRHOMA-β

Control149.16 ± 10.8895.70 ± 9.7011.0 ± 1.432.209 ± 0.52153 ± 11.6
Untreated HFD178.5 ± 14.33130.45 ± 15.2921.8 ± 2.776.09 ± 1.33102.86 ± 23.2
Treated HFD with BRB157.66 ± 11.80107.08 ± 3.8011.7 ± 1.162.73 ± 0.61118 ± 8.6
Protected HFD with BRB173.5 ± 15.87110.95 ± 4.2711.9 ± 1.782.72 ± 0.9193.4 ± 5.7

Mean value in each column having different superscript (a, b) is significant difference at .