Research Article

In Vivo Interrelationship between Insulin Resistance and Interferon Gamma Production: Protective and Therapeutic Effect of Berberine

Table 4

Effect of HFD alone or combined with berberine on cytokines profile, WBCs, and lymphocytes count.

GroupsIL-6 (pg/mL)IL-12 (ng/mL)IFN-γ (pg/mL)WBC 103LYMF

Control80.21 ± 4.13159.96 ± 13.1691.72 ± 11.856.7 ± 1.513.64 ± 0.47
Untreated HFD143.75 ± 13.62105.58 ± 13.9221.16 ± 1.115.6 ± 1.711.75 ± 0.71
Treated HFD with BRB91.08 ± 3.61153.46 ± 16.9649.32 ± 5.555.16 ± 1.112.15 ± 0.9
Protected HFD with BRB117.01 ± 7.92148.19 ± 18.7946.90 ± 6.175.96 ± 1.852.0 ± 0.66

Mean value in each column having different superscript (a, b, c, and d) is significant difference at .