Effects of Guchang Capsule on Dextran Sulphate Sodium-Induced Experimental Ulcerative Colitis in Mice

Figure 1

Effect of GC on body weight, DAI, and survival rate in DSS-treated mice. (a) Body weight change; (b) disease activity index; and (c) survival rate. Experimental model of ulcerative colitis was induced by administration of 4% dextran sulfate sodium (DSS) for 6 days and then switched to regular drinking water for data monitoring. GC were given intragastrically once per day for 6 days from the first day, respectively. Body weight change (a) and disease progression (b) were monitored daily from day 1 to day 7. Survival rate (c) was monitored until day 15 after the initiation of DSS. The data are representative of three independent experiments ( per group in (a-b) and per group in (c), mean ± SD). versus control + DSS group; versus control group.

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