Effects of Guchang Capsule on Dextran Sulphate Sodium-Induced Experimental Ulcerative Colitis in Mice

Figure 6

GC regulated NF-κB related lncRNAs expression. (a) QPCR analysis of lncRNA Lethe, lncRNA-Cox2, and lncRNA AS-IL1α expression in RAW264.7 cells after LPS (100 ng/mL) and GC (1 mg/mL) treatment for 4 hours; (b) qPCR analysis of lncRNA Lethe, lncRNA-Cox2, and lncRNA AS-IL1α mRNA level in mice after DSS (4%) and GC (2 g/kg) treatment for 6 days; (c) qPCR analysis of expression of lncRNA NKILA, lncRNA THRIL, and lncRNA-IL7R in THP-1-derived macrophages after LPS (100 ng/mL) and GC (1 mg/mL) treatment for 4 hours. The data are representative of three independent experiments ( per group in (b), mean ± SD). ; ; versus control + LPS (DSS) group.

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