Key Molecular Mechanisms of Chaiqinchengqi Decoction in Alleviating the Pulmonary Albumin Leakage Caused by Endotoxemia in Severe Acute Pancreatitis Rats

<div>Predicting target proteins for CQCQD to attenuate pulmonary albumin leakage based on the analyses of rats pulmonary tissue microarray and also the construction of PPI network. (a) The proteins, encoded by these prioritized hub nodes including Fos, Pik3r1, and Src, were predicted as the key target proteins (red nodes = upregulated DEGs, green nodes = downregulated DEGs, grey nodes = other interactive genes; the size of nodes = the betweenness of the node). (b) The expressions of these 3 prioritized hub nodes in each sample within each group (red represents upregulation and green represents downregulation).</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 2: Key Molecular Mechanisms of Chaiqinchengqi Decoction in Alleviating the Pulmonary Albumin Leakage Caused by Endotoxemia in Severe Acute Pancreatitis Rats 

Figure 2 | Key Molecular Mechanisms of Chaiqinchengqi Decoction in Alleviating the Pulmonary Albumin Leakage Caused by Endotoxemia in Severe Acute Pancreatitis Rats 