Cytotoxicity and Genotoxicity Assessment of Sandalwood Essential Oil in Human Breast Cell Lines MCF-7 and MCF-10A

Figure 5

Distribution of comet classes (DNA damage) in (a) MCF-7 and (b) MCF-10A cells. (c) DNA damage was calculated as DNA damage index. Sandalwood essential oil induces double-stranded breaks in the DNA of MCF-7 cells. However, the same effect is not seen in MCF-10A cells. Every bar represents the mean ± SEM of three independent experiments. Asterisks () denote statistical significance between the two cell lines upon treatment (Student’s -test).

(a)

(b)

(c)