The Use of Complementary and Alternative Medicine Supplements of Potential Concern during Breast Cancer Chemotherapy
Table 2
CAM during chemotherapy (ref. natural medicines comprehensive database) .
Capecitabine
Carboplatin
Cyclophosphamide (IV)
Cyclophosphamide (PO)
Docetaxel
Doxorubicin
Lapatinib
Methotrexate
Vinorelbine
5-FU
Radiation
Total
Antioxidants
Alpha-lipoic acid
0 (0.0)
2 (5.3)
6 (3.6)
0 (0.0)
6 (5.9)
1 (1.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
6 (2.4)
11 (3.1)
Beta carotene
3 (1.2)
3 (0.9)
CoQ10
0 (0.0)
7 (18.4)
12 (7.2)
0 (0.0)
9 (8.9)
9 (8.6)
1 (33.3)
0 (0.0)
0 (0.0)
0 (0.0)
13 (5.2)
27 (7.7)
Glutathione
1 (0.4)
1 (0.3)
Grape seed extract
1 (0.4)
1 (0.3)
Green tea
33 (19.8)
0 (0.0)
0 (0.0)
34 (13.5)
55 (15.7)
Lycopene
0 (0.0)
0 (0.0)
Melatonin
25 (15.0)
0 (0.0)
23 (9.2)
38 (10.8)
Pycnogenol
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
Resveratrol
2 (1.2)
0 (0.0)
2 (2.0)
0 (0.0)
1 (0.4)
3 (0.9)
Selenium
4 (1.6)
4 (1.1)
Turmeric
15 (9.0)
1 (6.7)
9 (8.9)
9 (8.6)
1 (33.3)
0 (0.0)
11 (4.4)
26 (7.4)
Vitamin A
9 (5.4)
2 (13.3)
2 (14.3)
15 (6.0)
20 (5.7)
Vitamin C
0 (0.0)
7 (18.4)
16 (9.6)
3 (20.0)
9 (8.9)
10 (9.5)
1 (33.3)
3 (21.4)
0 (0.0)
3 (18.8)
23 (9.2)
40 (11.4)
Vitamin E
0 (0.0)
7 (18.4)
16 (9.6)
2 (13.3)
12 (11.9)
8 (7.6)
0 (0.0)
2 (14.3)
0 (0.0)
2 (12.5)
21 (8.4)
37 (10.6)
Any of the above antioxidants
0 (0.0)
15 (39.5)
64 (38.3)
4 (26.7)
28 (27.7)
24 (22.9)
1 (33.3)
3 (21.4)
0 (0.0)
3 (18.8)
77 (30.7)
126 (36.0)
CYP activity
Bitter orange
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
Black cohosh
3 (1.8)
0 (0.0)
0 (0.0)
3 (1.3)
Dandelion
2 (1.9)
1 (33.3)
3 (1.3)
Devil’s claw
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
DHEA
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
Echinacea
1 (0.6)
1 (6.7)
0 (0.0)
1 (1.0)
0 (0.0)
0 (0.0)
2 (0.8)
Feverfew
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
Garlic
7 (6.9)
10 (9.5)
1 (33.3)
0 (0.0)
0 (0.0)
18 (7.6)
Genistein
0 (0.0)
0 (0.0)
0 (0.0)
Ginkgo biloba
2 (1.2)
0 (0.0)
1 (1.0)
1 (1.0)
0 (0.0)
0 (0.0)
0 (0.0)
2 (0.8)
Goldenseal
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
Grapefruit juice
1 (0.6)
0 (0.0)
1 (1.0)
1 (1.0)
0 (0.0)
0 (0.0)
0 (0.0)
2 (0.8)
Green tea
33 (19.8)
0 (0.0)
0 (0.0)
33 (13.9)
Guggul tree
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
Kava kava
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
Licorice
4 (2.4)
1 (6.7)
4 (3.8)
1 (33.3)
0 (0.0)
5 (2.1)
Milk thistle
3 (1.8)
0 (0.0)
3 (3.0)
1 (1.0)
1 (33.3)
0 (0.0)
5 (2.1)
Peppermint oil
3 (1.8)
0 (0.0)
2 (2.0)
0 (0.0)
0 (0.0)
0 (0.0)
3 (1.3)
Pycnogenol
0 (0.0)
0 (0.0)
0 (0.0)
Quercetin
6 (3.6)
0 (0.0)
1 (1.0)
5 (4.8)
1 (33.3)
0 (0.0)
7 (2.9)
Red clover
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
Resveratrol
2 (1.2)
0 (0.0)
2 (2.0)
1 (1.0)
0 (0.0)
0 (0.0)
3 (1.3)
Schisandra
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
St. John’s Wort
1 (0.6)
0 (0.0)
0 (0.0)
1 (1.0)
0 (0.0)
0 (0.0)
0 (0.0)
1 (0.4)
Valerian
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
Vitamin E
16 (9.6)
2 (13.3)
12 (11.9)
23 (9.7)
Any of the above CYP
0 (0.0)
0 (0.0)
50 (29.9)
3 (20.0)
23 (22.8)
22 (20.9)
2 (66.7)
0 (0.0)
0 (0.0)
0 (0.0)
68 (28.6)
Any of the above
0 (0.0)
15 (39.5)
67 (40.1)
5 (33.3)
35 (34.6)
36 (34.3)
2 (66.7)
3 (21.4)
0 (0.0)
3 (18.8)
77 (30.7)
104 (43.7)
Total is chemotherapy patients who took at least one of the named chemo drugs or had radiation therapy at the time the baseline questionnaire was filled out.
