Evaluation of Hepatoprotective Activity of Adansonia digitata Extract on Acetaminophen-Induced Hepatotoxicity in Rats

Table 1

Effect of Adansonia digitata extract on serum liver enzymes (ALT, AST, and ALP), total bilirubin, and total protein in acetaminophen-induced liver damage in rats.

Group	Regimen	ALT (IU/L)	AST (IU/L)	ALP (IU/L)	Total Bilirubin; (mg/dL)	Total Protein; (mg/dL)
I	Normal	57.4 ± 0.32	80.3 ± 0.60	130.5 ± 0.25	1.27 ± 0.20	9.8 ± 0.33
II	Acetaminophen	190.3 ± 0.24	123.5 ± 0.74	220.8 ± 0.55	3.29 ±0.90	4.6 ± 0.67
III	Acetaminophen + silymarin	60.6 ± 0.22^#	89.4 ± 0.29^#	145.9 ± 0.73^#	1.77 ± 0.48^#	7.8 ± 0.79^#
IV	Acetaminophen + extract	65.4 ± 0.11^#	95.6 ± 0.82^#	150.7 ± 0.67^#	2.00 ± 0.60^#	6.9 ± 0.61^#

Results were expressed as mean ± SD and analyzed using one-way ANOVA followed by Bonferroni’s post hoc test.
⁢ compared to normal control group.
^# compared to acetaminophen group, .