Research Article

Intravenous Mistletoe Treatment in Integrative Cancer Care: A Qualitative Study Exploring the Procedures, Concepts, and Observations of Expert Doctors

Box 1

Examples of how the doctors applied infusions with different preparations.
Abnoba Viscum
Characteristics:
(i) Favored for an initial high-dose fever-inducing treatment, combining i.v. and s.c. application.
Application:
Infusions added to a subcutaneous application:
(i) Low starting dose between 0.2 and 10 mg (rarely 20–40 mg) or last subcutaneous dose.
(ii) Stepwise dose increase, depending on the tolerability, up to 20–40 mg or to 160–200 mg as a maintenance dose.
(iii) Mostly applied weekly.
For high-dose therapy induction (no prior mistletoe contact):
(i) Infusions are started on three consecutive days (Fraxini 40–80–160 mg), combined with subcutaneous injection to induce fever
(e.g., 10 mg day 1 or 3 or else) and, if possible, also intratumoral application.
(ii) A subcutaneous treatment and weekly or monthly infusions usually follow.
Helixor
Characteristics:
(i) Favored because of its good tolerability.
(ii) In progressive disease.
(iii) To support tolerability of chemotherapy.
(iv) To relieve pain from bone metastases and fatigue.
Application
(i) Mali is often used in the host tree, such as in cachectic and metastatic situations. Pini is also used occasionally.
(ii) Mostly a low starting dose of 100, 200 or 300 mg, stepwise increased up to 600 mg, depending on tolerability.
(iii) Rarely increased up to 5–7 g.
(iv) A 5–10 mg initial dose in very sensitive patients, increased up to 50–100 mg.
Daily application in weak patients and patients at the progressive disease stage, decreased to biweekly application later.
For pain, 3-4 infusions are given on consecutive days. Three infusions per week are administered for fatigue.
Iscador
Characteristics
(i) Favored for repeated fever induction or temperature response.
Application
(i) For fever induction, the dosage has to be high enough and infusion time long enough. For instance: Iscador M or Qu, 5 mg
(“Spezial”) followed by a stepwise increase to 20–40 mg.
(ii) Host trees may be combined.
(iii) Applied once or twice per week initially and eventually every second week.
(iv) Daily infusions are too strenuous.